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What combines best with GLP-1 for obesity treatment: GIP receptor agonists or antagonists?
Lu et al.(1) previously demonstrated that antagonist antibodies against the GIP receptor promote weight loss combined with GLP-1. They now elegantly developed a conjugate of GIPR antibodies and GLP-1 and show effective weight loss in obese non-human primates.
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Elsevier
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8149460/ https://www.ncbi.nlm.nih.gov/pubmed/34095885 http://dx.doi.org/10.1016/j.xcrm.2021.100284 |