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Pharmacological Modulators of Small GTPases of Rho Family in Neurodegenerative Diseases

Classical Rho GTPases, including RhoA, Rac1, and Cdc42, are members of the Ras small GTPase superfamily and play essential roles in a variety of cellular functions. Rho GTPase signaling can be turned on and off by specific GEFs and GAPs, respectively. These features empower Rho GTPases and their ups...

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Detalles Bibliográficos
Autores principales: Guiler, William, Koehler, Addison, Boykin, Christi, Lu, Qun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8149604/
https://www.ncbi.nlm.nih.gov/pubmed/34054432
http://dx.doi.org/10.3389/fncel.2021.661612