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Therapeutic Development for CGG Repeat Expansion-Associated Neurodegeneration

Non-coding repeat expansions, such as CGG, GGC, CUG, CCUG, and GGGGCC, have been shown to be involved in many human diseases, particularly neurological disorders. Of the diverse pathogenic mechanisms proposed in these neurodegenerative diseases, dysregulated RNA metabolism has emerged as an importan...

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Detalles Bibliográficos
Autores principales: Xu, Keqin, Li, Yujing, Allen, Emily G., Jin, Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8149615/
https://www.ncbi.nlm.nih.gov/pubmed/34054431
http://dx.doi.org/10.3389/fncel.2021.655568