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OTUD7B stabilizes estrogen receptor α and promotes breast cancer cell proliferation

Breast cancer is the most common malignancy in women worldwide. Estrogen receptor α (ERα) is expressed in ∼70% of breast cancer cases and promotes estrogen-dependent cancer progression. In the present study, we identified OTU domain-containing 7B (OTUD7B), a deubiquitylase belonging to A20 subgroup...

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Detalles Bibliográficos
Autores principales: Tang, Jianing, Wu, Zeyu, Tian, Zelin, Chen, Wei, Wu, Gaosong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8149656/
https://www.ncbi.nlm.nih.gov/pubmed/34035221
http://dx.doi.org/10.1038/s41419-021-03785-7