High-throughput screening identifies a novel natural product-inspired scaffold capable of inhibiting Clostridioides difficile in vitro

Clostridioides difficile is an enteric pathogen responsible for causing debilitating diarrhea, mostly in hospitalized patients. The bacterium exploits on microbial dysbiosis induced by the use of antibiotics to establish infection that ranges from mild watery diarrhea to pseudomembranous colitis. Th...

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Detalles Bibliográficos
Autores principales: Pal, Rusha, Dai, Mingji, Seleem, Mohamed N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8149678/
https://www.ncbi.nlm.nih.gov/pubmed/34035338
http://dx.doi.org/10.1038/s41598-021-90314-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8149678/
https://www.ncbi.nlm.nih.gov/pubmed/34035338
http://dx.doi.org/10.1038/s41598-021-90314-3

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