Cryo-EM structure of type 1 IP(3)R channel in a lipid bilayer

Type 1 inositol 1,4,5-trisphosphate receptor (IP(3)R1) is the predominant Ca(2+)-release channel in neurons. IP(3)R1 mediates Ca(2+) release from the endoplasmic reticulum into the cytosol and thereby is involved in many physiological processes. Here, we present the cryo-EM structures of full-length...

Descripción completa

Detalles Bibliográficos
Autores principales: Baker, Mariah R., Fan, Guizhen, Seryshev, Alexander B., Agosto, Melina A., Baker, Matthew L., Serysheva, Irina I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8149723/
https://www.ncbi.nlm.nih.gov/pubmed/34035440
http://dx.doi.org/10.1038/s42003-021-02156-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8149723/
https://www.ncbi.nlm.nih.gov/pubmed/34035440
http://dx.doi.org/10.1038/s42003-021-02156-4

Ejemplares similares