Cargando…

Cryo-EM structure of type 1 IP(3)R channel in a lipid bilayer

Type 1 inositol 1,4,5-trisphosphate receptor (IP(3)R1) is the predominant Ca(2+)-release channel in neurons. IP(3)R1 mediates Ca(2+) release from the endoplasmic reticulum into the cytosol and thereby is involved in many physiological processes. Here, we present the cryo-EM structures of full-length...

Descripción completa

Detalles Bibliográficos
Autores principales:	Baker, Mariah R., Fan, Guizhen, Seryshev, Alexander B., Agosto, Melina A., Baker, Matthew L., Serysheva, Irina I.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8149723/ https://www.ncbi.nlm.nih.gov/pubmed/34035440 http://dx.doi.org/10.1038/s42003-021-02156-4

Ejemplares similares

Cryo-EM reveals ligand induced allostery underlying InsP(3)R channel gating
por: Fan, Guizhen, et al.
Publicado: (2018)

Single-Particle Cryo-EM of the Ryanodine Receptor Channel in an Aqueous Environment
por: Baker, Mariah R., et al.
Publicado: (2015)

Conformational motions and ligand-binding underlying gating and regulation in IP(3)R channel
por: Fan, Guizhen, et al.
Publicado: (2022)

Identification of ATP-Binding Regions in the RyR1 Ca(2+) Release Channel
por: Popova, Olga B., et al.
Publicado: (2012)

CryoEM reveals how the complement membrane attack complex ruptures lipid bilayers
por: Menny, Anaïs, et al.
Publicado: (2018)

AlphaFold2 and CryoEM: Revisiting CryoEM modeling in near-atomic resolution density maps
por: Hryc, Corey F., et al.
Publicado: (2022)

Cryo-EM structure of the BK potassium channel in a lipid membrane
por: Wang, Liguo, et al.
Publicado: (2009)

Segregation of lipids near acetylcholine-receptor channels imaged by cryo-EM
por: Unwin, Nigel
Publicado: (2017)

Single-particle cryo-EM reveals conformational variability of the oligomeric VCC β-barrel pore in a lipid bilayer
por: Sengupta, Nayanika, et al.
Publicado: (2021)

Cryo-EM structure of the human α1β3γ2 GABA(A) receptor in a lipid bilayer
por: Laverty, Duncan, et al.
Publicado: (2019)

Cryo-EM structure of the protein-conducting ERAD channel Hrd1 in complex with Hrd3
por: Schoebel, Stefan, et al.
Publicado: (2017)

Structure of the full-length TRPV2 channel by cryo-EM
por: Huynh, Kevin W., et al.
Publicado: (2016)

Architecture of the baculovirus nucleocapsid revealed by cryo-EM
por: Jia, Xudong, et al.
Publicado: (2023)

Optimization of cryo-electron microscopy for quantitative analysis of lipid bilayers
por: Heberle, Frederick A., et al.
Publicado: (2022)

Single-particle cryo-EM structure of a voltage-activated potassium channel in lipid nanodiscs
por: Matthies, Doreen, et al.
Publicado: (2018)

Cryo-EM of the dynamin polymer assembled on lipid membrane
por: Kong, Leopold, et al.
Publicado: (2018)

Beyond the Backbone: The Next Generation of Pathwalking Utilities for Model Building in CryoEM Density Maps
por: Hryc, Corey F., et al.
Publicado: (2022)

Cryo-EM structure of the calcium homeostasis modulator 1 channel
por: Ren, Yue, et al.
Publicado: (2020)

Cryo-EM structure of human heptameric pannexin 2 channel
por: Zhang, Hang, et al.
Publicado: (2023)

To Be or Not to Be an Ion Channel: Cryo-EM Structures Have a Say
por: Chen, Gui-Lan, et al.
Publicado: (2023)

Cryo-EM structure of the SARS-CoV-2 3a ion channel in lipid nanodiscs
por: Kern, David M., et al.
Publicado: (2021)

Ab Initio Modeling of the Herpesvirus VP26 Core Domain Assessed by CryoEM Density
por: Baker, Matthew L, et al.
Publicado: (2006)

Functional determination of calcium-binding sites required for the activation of inositol 1,4,5-trisphosphate receptors
por: Arige, Vikas, et al.
Publicado: (2022)

Cryo-EM structure of mouse TRPML2 in lipid nanodiscs
por: Song, Xiaojing, et al.
Publicado: (2021)

Cryo-EM structures of the channelrhodopsin ChRmine in lipid nanodiscs
por: Tucker, Kyle, et al.
Publicado: (2022)

Cryo-EM structures of the DCPIB-inhibited volume-regulated anion channel LRRC8A in lipid nanodiscs
por: Kern, David M, et al.
Publicado: (2019)

Fluorescence Approaches for Characterizing Ion Channels in Synthetic Bilayers
por: Islam, Md. Sirajul, et al.
Publicado: (2021)

Cryo-EM structure of the polycystin 2-l1 ion channel
por: Hulse, Raymond E, et al.
Publicado: (2018)

Structure of an innexin gap junction channel and cryo-EM sample preparation
por: Oshima, Atsunori
Publicado: (2017)

Cryo-EM analysis of PIP(2) regulation in mammalian GIRK channels
por: Niu, Yiming, et al.
Publicado: (2020)

Cryo-EM structures and functional properties of CALHM channels of the human placenta
por: Drożdżyk, Katarzyna, et al.
Publicado: (2020)

Small molecule modulation of the Drosophila Slo channel elucidated by cryo-EM
por: Raisch, Tobias, et al.
Publicado: (2021)

Cryo-EM structure of the heptameric calcium homeostasis modulator 1 channel
por: Ren, Yue, et al.
Publicado: (2022)

Cryo-EM structure of the plant 26S proteasome
por: Kandolf, Susanne, et al.
Publicado: (2022)

Cryo-EM structures of the human surfactant lipid transporter ABCA3
por: Xie, Tian, et al.
Publicado: (2022)

Unveiling Liquid-Crystalline Lipids in the Urothelial Membrane through Cryo-EM
por: Yanagisawa, Haruaki, et al.
Publicado: (2023)

Unveiling Liquid-Crystalline Lipids in the Urothelial Membrane through Cryo-EM
por: Oda, Toshiyuki, et al.
Publicado: (2023)

Cryo-EM structure of the diapause chaperone artemin
por: Parvate, Amar D., et al.
Publicado: (2022)

Cryo-EM structure of the ATP-sensitive potassium channel illuminates mechanisms of assembly and gating
por: Martin, Gregory M, et al.
Publicado: (2017)

A snapshot of cryo‐EM
por: Skiniotis, Georgios
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_e65he575icpcu6v8e4ifb6tps1