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The Emerging Application of Itaconate: Promising Molecular Targets and Therapeutic Opportunities

Metabolites have recently been found to be involved in significant biological regulation and changes. Itaconate, an important intermediate metabolite isolated from the tricarboxylic acid cycle, is derived from cis-aconitate decarboxylation mediated by immune response gene 1 in mitochondrial matrix....

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Detalles Bibliográficos
Autores principales: Lin, Jiaqi, Ren, Jinxuan, Gao, Dave Schwinn, Dai, Yi, Yu, Lina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8149739/
https://www.ncbi.nlm.nih.gov/pubmed/34055739
http://dx.doi.org/10.3389/fchem.2021.669308