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The Emerging Application of Itaconate: Promising Molecular Targets and Therapeutic Opportunities
Metabolites have recently been found to be involved in significant biological regulation and changes. Itaconate, an important intermediate metabolite isolated from the tricarboxylic acid cycle, is derived from cis-aconitate decarboxylation mediated by immune response gene 1 in mitochondrial matrix....
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8149739/ https://www.ncbi.nlm.nih.gov/pubmed/34055739 http://dx.doi.org/10.3389/fchem.2021.669308 |