Activation of Prp28 ATPase by phosphorylated Npl3 at a critical step of spliceosome remodeling

Splicing, a key step in the eukaryotic gene-expression pathway, converts precursor messenger RNA (pre-mRNA) into mRNA by excising introns and ligating exons. This task is accomplished by the spliceosome, a macromolecular machine that must undergo sequential conformational changes to establish its ac...

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Detalles Bibliográficos
Autores principales: Yeh, Fu-Lung, Chang, Shang-Lin, Ahmed, Golam Rizvee, Liu, Hsin-I, Tung, Luh, Yeh, Chung-Shu, Lanier, Leah Stands, Maeder, Corina, Lin, Che-Min, Tsai, Shu-Chun, Hsiao, Wan-Yi, Chang, Wei-Hau, Chang, Tien-Hsien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8149812/
https://www.ncbi.nlm.nih.gov/pubmed/34035302
http://dx.doi.org/10.1038/s41467-021-23459-4

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