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FOXM1 repression increases mitotic death upon antimitotic chemotherapy through BMF upregulation

Inhibition of spindle microtubule (MT) dynamics has been effectively used in cancer treatment. Although the mechanisms by which MT poisons elicit mitotic arrest are fairly understood, efforts are still needed towards elucidating how cancer cells respond to antimitotic drugs owing to cytotoxicity and...

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Detalles Bibliográficos
Autores principales: Vaz, Sara, Ferreira, Fábio J., Macedo, Joana C., Leor, Gil, Ben-David, Uri, Bessa, José, Logarinho, Elsa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8149823/
https://www.ncbi.nlm.nih.gov/pubmed/34035233
http://dx.doi.org/10.1038/s41419-021-03822-5