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Longitudinal analysis of blood markers reveals progressive loss of resilience and predicts human lifespan limit

We investigated the dynamic properties of the organism state fluctuations along individual aging trajectories in a large longitudinal database of CBC measurements from a consumer diagnostics laboratory. To simplify the analysis, we used a log-linear mortality estimate from the CBC variables as a sin...

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Detalles Bibliográficos
Autores principales: Pyrkov, Timothy V., Avchaciov, Konstantin, Tarkhov, Andrei E., Menshikov, Leonid I., Gudkov, Andrei V., Fedichev, Peter O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8149842/
https://www.ncbi.nlm.nih.gov/pubmed/34035236
http://dx.doi.org/10.1038/s41467-021-23014-1