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CBX7 suppresses urinary bladder cancer progression via modulating AKR1B10–ERK signaling

The chromobox (CBX) proteins mediate epigenetic gene silencing and have been implicated in the cancer development. By analyzing eight CBX family members in TCGA dataset, we found that chromobox 7 (CBX7) was the most strikingly downregulated CBX family member in urinary bladder cancer (UBC), as compa...

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Detalles Bibliográficos
Autores principales: Huang, Zhengnan, Yan, Yilin, Zhu, Zhen, Liu, Jiakuan, He, Xiao, Dalangood, Sumiya, Li, Meiqian, Tan, Mingyue, Cai, Jinming, Tang, Pengfei, Huang, Ruimin, Shen, Bing, Yan, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8149849/
https://www.ncbi.nlm.nih.gov/pubmed/34035231
http://dx.doi.org/10.1038/s41419-021-03819-0