Muscle regeneration controlled by a designated DNA dioxygenase

Tet dioxygenases are responsible for the active DNA demethylation. The functions of Tet proteins in muscle regeneration have not been well characterized. Here we find that Tet2, but not Tet1 and Tet3, is specifically required for muscle regeneration in vivo. Loss of Tet2 leads to severe muscle regen...

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Detalles Bibliográficos
Autores principales: Wang, Hongye, Huang, Yile, Yu, Ming, Yu, Yang, Li, Sheng, Wang, Huating, Sun, Hao, Li, Bing, Xu, Guoliang, Hu, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8149877/
https://www.ncbi.nlm.nih.gov/pubmed/34035232
http://dx.doi.org/10.1038/s41419-021-03817-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8149877/
https://www.ncbi.nlm.nih.gov/pubmed/34035232
http://dx.doi.org/10.1038/s41419-021-03817-2

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