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Muscle regeneration controlled by a designated DNA dioxygenase
Tet dioxygenases are responsible for the active DNA demethylation. The functions of Tet proteins in muscle regeneration have not been well characterized. Here we find that Tet2, but not Tet1 and Tet3, is specifically required for muscle regeneration in vivo. Loss of Tet2 leads to severe muscle regen...
Autores principales: | Wang, Hongye, Huang, Yile, Yu, Ming, Yu, Yang, Li, Sheng, Wang, Huating, Sun, Hao, Li, Bing, Xu, Guoliang, Hu, Ping |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8149877/ https://www.ncbi.nlm.nih.gov/pubmed/34035232 http://dx.doi.org/10.1038/s41419-021-03817-2 |
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