Deciphering the scopolamine challenge rat model by preclinical functional MRI

During preclinical drug testing, the systemic administration of scopolamine (SCO), a cholinergic antagonist, is widely used. However, it suffers important limitations, like non-specific behavioural effects partly due to its peripheral side-effects. Therefore, neuroimaging measures would enhance its...

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Detalles Bibliográficos
Autores principales: Somogyi, Gergely, Hlatky, Dávid, Spisák, Tamás, Spisák, Zsófia, Nyitrai, Gabriella, Czurkó, András
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8149883/
https://www.ncbi.nlm.nih.gov/pubmed/34035328
http://dx.doi.org/10.1038/s41598-021-90273-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8149883/
https://www.ncbi.nlm.nih.gov/pubmed/34035328
http://dx.doi.org/10.1038/s41598-021-90273-9

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