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Essential genes from genome-wide screenings as a resource for neuropsychiatric disorders gene discovery

Genome-wide screenings of “essential genes”, i.e., genes required for an organism or cell survival, have been traditionally conducted in vitro in cancer cell lines, limiting the translation of results to other tissues and non-cancerous cells. Recently, an in vivo screening was conducted in adult mou...

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Detalles Bibliográficos
Autores principales: Zhang, Wei, Quevedo, Joao, Fries, Gabriel R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8149887/
https://www.ncbi.nlm.nih.gov/pubmed/34035214
http://dx.doi.org/10.1038/s41398-021-01447-y