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Essential genes from genome-wide screenings as a resource for neuropsychiatric disorders gene discovery
Genome-wide screenings of “essential genes”, i.e., genes required for an organism or cell survival, have been traditionally conducted in vitro in cancer cell lines, limiting the translation of results to other tissues and non-cancerous cells. Recently, an in vivo screening was conducted in adult mou...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8149887/ https://www.ncbi.nlm.nih.gov/pubmed/34035214 http://dx.doi.org/10.1038/s41398-021-01447-y |