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Differences in Maturation Status and Immune Phenotypes of Circulating Helios(+) and Helios(−) Tregs and Their Disrupted Correlations With Monocyte Subsets in Autoantibody-Positive T1D Individuals

CD4 Tregs are involved in the regulation of various autoimmune diseases but believed to be highly heterogeneous. Studies have indicated that Helios controls a distinct subset of functional Tregs. However, the immunological changes in circulating Helios(+) and Helios(−) Tregs are not fully explored i...

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Detalles Bibliográficos
Autores principales: Zhang, Yuyue, Zhang, Jie, Shi, Yun, Shen, Min, Lv, Hui, Chen, Shu, Feng, Yingjie, Chen, Heng, Xu, Xinyu, Yang, Tao, Xu, Kuanfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8149963/
https://www.ncbi.nlm.nih.gov/pubmed/34054801
http://dx.doi.org/10.3389/fimmu.2021.628504