Cargando…

α-Glucuronosyl and α-glucosyl diacylglycerides, natural killer T cell-activating lipids from bacteria and fungi

Natural killer T cells express T cell receptors (TCRs) that recognize glycolipid antigens in association with the antigen-presenting molecule CD1d. Here, we report the concise chemical synthesis of a range of saturated and unsaturated α-glucosyl and α-glucuronosyl diacylglycerides of bacterial and f...

Descripción completa

Detalles Bibliográficos
Autores principales: Burugupalli, Satvika, Almeida, Catarina F., Smith, Dylan G. M., Shah, Sayali, Patel, Onisha, Rossjohn, Jamie, Uldrich, Adam P., Godfrey, Dale I., Williams, Spencer J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8150115/
https://www.ncbi.nlm.nih.gov/pubmed/34123306
http://dx.doi.org/10.1039/c9sc05248h