Empirical Evaluation of the Use of Computational HLA Binding as an Early Filter to the Mass Spectrometry-Based Epitope Discovery Workflow

SIMPLE SUMMARY: Many different human leukocyte antigen (HLA)-types exist across the population that each binds a specific motif of amino acids. HLA-peptide complexes are the driving force behind recognition of cancers and infected cells by cytotoxic T cells. HLA-immunopeptidomics aims to identify pe...

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Detalles Bibliográficos
Autores principales: Bouzid, Rachid, de Beijer, Monique T. A., Luijten, Robbie J., Bezstarosti, Karel, Kessler, Amy L., Bruno, Marco J., Peppelenbosch, Maikel P., Demmers, Jeroen A. A., Buschow, Sonja I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8150281/
https://www.ncbi.nlm.nih.gov/pubmed/34065814
http://dx.doi.org/10.3390/cancers13102307

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8150281/
https://www.ncbi.nlm.nih.gov/pubmed/34065814
http://dx.doi.org/10.3390/cancers13102307

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