Cargando…

Empirical Evaluation of the Use of Computational HLA Binding as an Early Filter to the Mass Spectrometry-Based Epitope Discovery Workflow

SIMPLE SUMMARY: Many different human leukocyte antigen (HLA)-types exist across the population that each binds a specific motif of amino acids. HLA-peptide complexes are the driving force behind recognition of cancers and infected cells by cytotoxic T cells. HLA-immunopeptidomics aims to identify pe...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bouzid, Rachid, de Beijer, Monique T. A., Luijten, Robbie J., Bezstarosti, Karel, Kessler, Amy L., Bruno, Marco J., Peppelenbosch, Maikel P., Demmers, Jeroen A. A., Buschow, Sonja I.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8150281/ https://www.ncbi.nlm.nih.gov/pubmed/34065814 http://dx.doi.org/10.3390/cancers13102307

Ejemplares similares

Opportunities for Conventional and In Situ Cancer Vaccine Strategies and Combination with Immunotherapy for Gastrointestinal Cancers, A Review
por: Bouzid, Rachid, et al.
Publicado: (2020)

Immunopeptidome of hepatocytes isolated from patients with HBV infection and hepatocellular carcinoma
por: de Beijer, Monique T.A., et al.
Publicado: (2022)

Induction of broad multifunctional CD8+ and CD4+ T cells by hepatitis B virus antigen-based synthetic long peptides ex vivo
por: Jansen, Diahann T. S. L., et al.
Publicado: (2023)

Discovery and Selection of Hepatitis B Virus-Derived T Cell Epitopes for Global Immunotherapy Based on Viral Indispensability, Conservation, and HLA-Binding Strength
por: de Beijer, Monique T. A., et al.
Publicado: (2020)

Emerging organoid-immune co-culture models for cancer research: from oncoimmunology to personalized immunotherapies
por: Magré, Luc, et al.
Publicado: (2023)

Systemic T-cell and humoral responses against cancer testis antigens in hepatocellular carcinoma patients
por: Noordam, Lisanne, et al.
Publicado: (2022)

HLA-DQ-Specific Recombinant Human Monoclonal Antibodies Allow for In-Depth Analysis of HLA-DQ Epitopes
por: Bezstarosti, Suzanne, et al.
Publicado: (2022)

A Comprehensive Evaluation of the Antibody-Verified Status of Eplets Listed in the HLA Epitope Registry
por: Bezstarosti, Suzanne, et al.
Publicado: (2022)

Identification of Conserved and HLA Promiscuous DENV3 T-Cell Epitopes
por: Nascimento, Eduardo J. M., et al.
Publicado: (2013)

Site‐directed mutagenesis of HLA molecules reveals the functional epitope of a human HLA‐A1/A36‐specific monoclonal antibody
por: Meng, Tina, et al.
Publicado: (2022)

Lack of HLA predominance and HLA shared epitopes in biliary Atresia
por: Mack, Cara L, et al.
Publicado: (2013)

Measles Virus Epitope Presentation by HLA: Novel Insights into Epitope Selection, Dominance, and Microvariation
por: Schellens, Ingrid M., et al.
Publicado: (2015)

Kinome Profiling
por: Peppelenbosch, Maikel P.
Publicado: (2012)

Meeting report on the first Sino-Dutch symposium on oncology
por: Peppelenbosch, Maikel P.
Publicado: (2016)

Reflections on HLA Epitope-Based Matching for Transplantation
por: Duquesnoy, Rene J.
Publicado: (2016)

HLA Epitopes: The Targets of Monoclonal and Alloantibodies Defined
por: El-Awar, Nadim, et al.
Publicado: (2017)

Neoantigen Quantity and Quality in Relation to Pancreatic Cancer Survival
por: Levink, Iris J. M., et al.
Publicado: (2022)

The Potential of Soluble Human Leukocyte Antigen Molecules for Early Cancer Detection and Therapeutic Vaccine Design
por: Kessler, Amy L., et al.
Publicado: (2020)

A robust deep learning workflow to predict CD8 + T-cell epitopes
por: Lee, Chloe H., et al.
Publicado: (2023)

The Role of Mass Spectrometry and Proteogenomics in the Advancement of HLA Epitope Prediction
por: Creech, Amanda L., et al.
Publicado: (2018)

An Oct4-Centered Protein Interaction Network in Embryonic Stem Cells
por: van den Berg, Debbie L.C., et al.
Publicado: (2010)

The shared epitope revisited: shared epitope negative HLA-DR alleles influence susceptibility to rheumatoid arthritis
por: Reviron, D, et al.
Publicado: (2001)

FACT subunit Spt16 controls UVSSA recruitment to lesion-stalled RNA Pol II and stimulates TC-NER
por: Wienholz, Franziska, et al.
Publicado: (2019)

Direct analysis of HLA/HER-2 peptide epitopes
por: Patterson, Andrea, et al.
Publicado: (2013)

Recovery in the Myogenic Program of Congenital Myotonic Dystrophy Myoblasts after Excision of the Expanded (CTG)n Repeat
por: André, Laurène M., et al.
Publicado: (2019)

Distinct proteomic profiles in prefrontal subareas of elderly major depressive disorder and bipolar disorder patients
por: Qi, Yang-Jian, et al.
Publicado: (2022)

Independent Mechanisms Target SMCHD1 to Trimethylated Histone H3 Lysine 9-Modified Chromatin and the Inactive X Chromosome
por: Brideau, Nicholas J., et al.
Publicado: (2015)

Final Cut Pro workflows: the independent studio handbook
por: Osder, Jason, et al.
Publicado: (2008)

Hepatological coordination of pregnancy-related changes
por: Peppelenbosch, Maikel P., et al.
Publicado: (2021)

Microscopy-based single-cell proteomic profiling reveals heterogeneity in DNA damage response dynamics
por: Su, Pin-Rui, et al.
Publicado: (2022)

Targeted proteomics as a tool to detect SARS-CoV-2 proteins in clinical specimens
por: Bezstarosti, Karel, et al.
Publicado: (2021)

T-Cell Epitopes Shared Between Immunizing HLA and Donor HLA Associate With Graft Failure After Kidney Transplantation
por: Peereboom, Emma T. M., et al.
Publicado: (2021)

Semi-quantitative proteomics of mammalian cells upon short-term exposure to non-ionizing electromagnetic fields
por: Kuzniar, Arnold, et al.
Publicado: (2017)

Conservation and Diversity of Influenza A H1N1 HLA-Restricted T Cell Epitope Candidates for Epitope-Based Vaccines
por: Tan, Paul ThiamJoo, et al.
Publicado: (2010)

T-Epitope Designer: A HLA-peptide binding prediction server
por: Kangueane, Pandjassarame, et al.
Publicado: (2005)

In silico characterization of immunogenic epitopes presented by HLA-Cw*0401
por: Tong, Joo Chuan, et al.
Publicado: (2007)

Humoral Alloimmunity in Transplantation: Relevance of HLA Epitope Antigenicity and Immunogenicity
por: Duquesnoy, René J.
Publicado: (2011)

Comparing HLA Shared Epitopes in French Caucasian Patients with Scleroderma
por: Azzouz, Doua F., et al.
Publicado: (2012)

Adaptive Evolution of HIV at HLA Epitopes Is Associated with Ethnicity in Canada
por: Ragonnet-Cronin, Manon, et al.
Publicado: (2012)

Multiple HLA Epitopes Contribute to Type 1 Diabetes Susceptibility
por: Roark, Christina L., et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_fhg13bbstn9anirs8nvp92ivqs