Molecular Dynamic Simulations Suggest That Metabolite-Induced Post-Translational Modifications Alter the Behavior of the Fibrinogen Coiled-Coil Domain

Fibrinogen is an abundant blood plasma protein that, inter alia, participates in blood coagulation. It polymerizes to form a fibrin clot that is among the major components of the thrombus. Fibrinogen reactions with various reactive metabolites may induce post-translational modifications (PTMs) into...

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Detalles Bibliográficos
Autores principales: Sovova, Zofie, Suttnar, Jiri, Dyr, Jan E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8150326/
https://www.ncbi.nlm.nih.gov/pubmed/34065002
http://dx.doi.org/10.3390/metabo11050307

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8150326/
https://www.ncbi.nlm.nih.gov/pubmed/34065002
http://dx.doi.org/10.3390/metabo11050307

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