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The Role of p53 Dysfunction in Colorectal Cancer and Its Implication for Therapy

SIMPLE SUMMARY: Despite remarkable progress being made by preventive medical check-ups in the last decades, colorectal cancer (CRC) remains one of the most frequent and deadliest cancers worldwide. An understanding of the mutational landscape in CRC is needed to develop new mutanome-directed therapi...

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Detalles Bibliográficos
Autores principales: Michel, Maurice, Kaps, Leonard, Maderer, Annett, Galle, Peter R., Moehler, Markus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8150459/
https://www.ncbi.nlm.nih.gov/pubmed/34064974
http://dx.doi.org/10.3390/cancers13102296