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Ligand-induced structural changes analysis of ribose-binding protein as studied by molecular dynamics simulations

BACKGROUND: The ribose-binding protein (RBP) from Escherichia coli is one of the representative structures of periplasmic binding proteins. Binding of ribose at the cleft between two domains causes a conformational change corresponding to a closure of two domains around the ligand. The RBP has been...

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Detalles Bibliográficos
Autores principales: Li, Haiyan, Cao, Zanxia, Hu, Guodong, Zhao, Liling, Wang, Chunling, Wang, Jihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8150535/
https://www.ncbi.nlm.nih.gov/pubmed/33682750
http://dx.doi.org/10.3233/THC-218011