In Vivo Expression of Reprogramming Factor OCT4 Ameliorates Myelination Deficits and Induces Striatal Neuroprotection in Huntington’s Disease

White matter atrophy has been shown to precede the massive loss of striatal GABAergic neurons in Huntington’s disease (HD). This study investigated the effects of in vivo expression of reprogramming factor octamer-binding transcription factor 4 (OCT4) on neural stem cell (NSC) niche activation in th...

Descripción completa

Detalles Bibliográficos
Autores principales: Yu, Ji-Hea, Nam, Bae-Geun, Kim, Min-Gi, Pyo, Soonil, Seo, Jung-Hwa, Cho, Sung-Rae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8150572/
https://www.ncbi.nlm.nih.gov/pubmed/34068799
http://dx.doi.org/10.3390/genes12050712

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8150572/
https://www.ncbi.nlm.nih.gov/pubmed/34068799
http://dx.doi.org/10.3390/genes12050712

Ejemplares similares