Cargando…

KRAS, A Prime Mediator in Pancreatic Lipid Synthesis through Extra Mitochondrial Glutamine and Citrate Metabolism

Kirsten rat sarcoma viral oncogene homolog (KRAS)-driven pancreatic cancer is very lethal, with a five-year survival rate of <9%, irrespective of therapeutic advances. Different treatment modalities including chemotherapy, radiotherapy, and immunotherapy demonstrated only marginal efficacies beca...

Descripción completa

Detalles Bibliográficos
Autores principales: Muyinda, Isaac James, Park, Jae-Gwang, Jang, Eun-Jung, Yoo, Byong-Chul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8150642/
https://www.ncbi.nlm.nih.gov/pubmed/34064761
http://dx.doi.org/10.3390/ijms22105070