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Plasma Metabolomics Analysis of Polyvinyl Chloride Workers Identifies Altered Processes and Candidate Biomarkers for Hepatic Hemangiosarcoma and Its Development

Background: High-level occupational vinyl chloride (VC) exposures have been associated with hepatic hemangiosarcoma, which typically develops following a long latency period. Although VC is genotoxic, a more comprehensive mode of action has not been determined and diagnostic biomarkers have not been...

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Detalles Bibliográficos
Autores principales: Guardiola, John J., Hardesty, Josiah E., Beier, Juliane I., Prough, Russell A., McClain, Craig J., Cave, Matthew C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8150673/
https://www.ncbi.nlm.nih.gov/pubmed/34065028
http://dx.doi.org/10.3390/ijms22105093