The Rab7 effector WDR91 promotes autophagy-lysosome degradation in neurons by regulating lysosome fusion

The effectors of the Rab7 small GTPase play multiple roles in Rab7-dependent endosome-lysosome and autophagy-lysosome pathways. However, it is largely unknown how distinct Rab7 effectors coordinate to maintain the homeostasis of late endosomes and lysosomes to ensure appropriate endolysosomal and au...

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Detalles Bibliográficos
Autores principales: Xing, Ruxiao, Zhou, Hejiang, Jian, Youli, Li, Lingling, Wang, Min, Liu, Nan, Yin, Qiuyuan, Liang, Ziqi, Guo, Weixiang, Yang, Chonglin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8150682/
https://www.ncbi.nlm.nih.gov/pubmed/34028500
http://dx.doi.org/10.1083/jcb.202007061

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8150682/
https://www.ncbi.nlm.nih.gov/pubmed/34028500
http://dx.doi.org/10.1083/jcb.202007061

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