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Syndecan-1 Promotes Angiogenesis in Triple-Negative Breast Cancer through the Prognostically Relevant Tissue Factor Pathway and Additional Angiogenic Routes

SIMPLE SUMMARY: Triple-negative breast cancer is an aggressive subtype of breast cancer characterized by tumor angiogenesis and poor patient survival. Here, we analyzed the function of the cell surface molecule Syndecan-1 in tumor angiogenesis in a 3D cell culture system. As a novel finding, we demo...

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Detalles Bibliográficos
Autores principales: Nassar, Eyyad, Hassan, Nourhan, El-Ghonaimy, Eslam A., Hassan, Hebatallah, Abdullah, Mahmoud Salah, Rottke, Theresa V., Kiesel, Ludwig, Greve, Burkhard, Ibrahim, Sherif Abdelaziz, Götte, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8150756/
https://www.ncbi.nlm.nih.gov/pubmed/34066023
http://dx.doi.org/10.3390/cancers13102318