Cargando…
Syndecan-1 Promotes Angiogenesis in Triple-Negative Breast Cancer through the Prognostically Relevant Tissue Factor Pathway and Additional Angiogenic Routes
SIMPLE SUMMARY: Triple-negative breast cancer is an aggressive subtype of breast cancer characterized by tumor angiogenesis and poor patient survival. Here, we analyzed the function of the cell surface molecule Syndecan-1 in tumor angiogenesis in a 3D cell culture system. As a novel finding, we demo...
Autores principales: | Nassar, Eyyad, Hassan, Nourhan, El-Ghonaimy, Eslam A., Hassan, Hebatallah, Abdullah, Mahmoud Salah, Rottke, Theresa V., Kiesel, Ludwig, Greve, Burkhard, Ibrahim, Sherif Abdelaziz, Götte, Martin |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8150756/ https://www.ncbi.nlm.nih.gov/pubmed/34066023 http://dx.doi.org/10.3390/cancers13102318 |
Ejemplares similares
-
Syndecan-1 is a novel molecular marker for triple negative inflammatory breast cancer and modulates the cancer stem cell phenotype via the IL-6/STAT3, Notch and EGFR signaling pathways
por: Ibrahim, Sherif Abdelaziz, et al.
Publicado: (2017) -
The Cell Surface Heparan Sulfate Proteoglycan Syndecan-3 Promotes Ovarian Cancer Pathogenesis
por: Hillemeyer, Lara, et al.
Publicado: (2022) -
Differential Impact of Membrane-Bound and Soluble Forms of the Prognostic Marker Syndecan-1 on the Invasiveness, Migration, Apoptosis, and Proliferation of Cervical Cancer Cells
por: Hilgers, Katharina, et al.
Publicado: (2022) -
Induction of heparanase via IL-10 correlates with a high infiltration of CD163+ M2-type tumor-associated macrophages in inflammatory breast carcinomas
por: El-Nadi, Mennatullah, et al.
Publicado: (2020) -
Syndecan-1 (CD138) Modulates Triple-Negative Breast Cancer Stem Cell Properties via Regulation of LRP-6 and IL-6-Mediated STAT3 Signaling
por: Ibrahim, Sherif A., et al.
Publicado: (2013)