A Pharmacogenetic Study of CYP2C19 in Acute Coronary Syndrome Patients of Colombian Origin Reveals New Polymorphisms Potentially Related to Clopidogrel Therapy

Clopidogrel, an oral platelet P2Y(12) receptor blocker, is used in the treatment of acute coronary syndrome. Interindividual variability in treatment response and the occurrence of adverse effects has been attributed to genetic variants in CYP2C19. The analysis of relevant pharmacogenes in ethnicall...

Descripción completa

Detalles Bibliográficos
Autores principales: Angulo-Aguado, Mariana, Panche, Karen, Tamayo-Agudelo, Caroll Andrea, Ruiz-Torres, Daniel-Armando, Sambracos-Parrado, Santiago, Niño-Orrego, Maria Jose, Páez, Nathaly, Piñeros-Hernandez, Laura B, Castillo-León, Luisa-Fernanda, Pardo-Oviedo, Juan Mauricio, Abaunza, Katherine Parra, Laissue, Paul, Contreras, Nora, Calderón-Ospina, Carlos Alberto, Fonseca-Mendoza, Dora Janeth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8150782/
https://www.ncbi.nlm.nih.gov/pubmed/34065778
http://dx.doi.org/10.3390/jpm11050400

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8150782/
https://www.ncbi.nlm.nih.gov/pubmed/34065778
http://dx.doi.org/10.3390/jpm11050400

Ejemplares similares