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Deregulation of Ca(2+)-Signaling Systems in White Adipocytes, Manifested as the Loss of Rhythmic Activity, Underlies the Development of Multiple Hormonal Resistance at Obesity and Type 2 Diabetes
Various types of cells demonstrate ubiquitous rhythmicity registered as simple and complex Ca(2+)-oscillations, spikes, waves, and triggering phenomena mediated by G-protein and tyrosine kinase coupled receptors. Phospholipase C/IP(3)-receptors (PLC/IP(3)R) and endothelial NO-synthase/Ryanodine rece...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8150837/ https://www.ncbi.nlm.nih.gov/pubmed/34065973 http://dx.doi.org/10.3390/ijms22105109 |