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Deregulation of Ca(2+)-Signaling Systems in White Adipocytes, Manifested as the Loss of Rhythmic Activity, Underlies the Development of Multiple Hormonal Resistance at Obesity and Type 2 Diabetes

Various types of cells demonstrate ubiquitous rhythmicity registered as simple and complex Ca(2+)-oscillations, spikes, waves, and triggering phenomena mediated by G-protein and tyrosine kinase coupled receptors. Phospholipase C/IP(3)-receptors (PLC/IP(3)R) and endothelial NO-synthase/Ryanodine rece...

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Detalles Bibliográficos
Autores principales: Turovsky, Egor A., Turovskaya, Maria V., Dynnik, Vladimir V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8150837/
https://www.ncbi.nlm.nih.gov/pubmed/34065973
http://dx.doi.org/10.3390/ijms22105109