Exploring the Release of Toxic Oligomers from α-Synuclein Fibrils with Antibodies and STED Microscopy

α-Synuclein (αS) is an intrinsically disordered and highly dynamic protein involved in dopamine release at presynaptic terminals. The abnormal aggregation of αS as mature fibrils into intraneuronal inclusion bodies is directly linked to Parkinson’s disease. Increasing experimental evidence suggests...

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Detalles Bibliográficos
Autores principales: Bigi, Alessandra, Ermini, Emilio, Chen, Serene W., Cascella, Roberta, Cecchi, Cristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8150853/
https://www.ncbi.nlm.nih.gov/pubmed/34064766
http://dx.doi.org/10.3390/life11050431

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8150853/
https://www.ncbi.nlm.nih.gov/pubmed/34064766
http://dx.doi.org/10.3390/life11050431

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