Initiation of Pancreatic Cancer: The Interplay of Hyperglycemia and Macrophages Promotes the Acquisition of Malignancy-Associated Properties in Pancreatic Ductal Epithelial Cells

Pancreatic ductal adenocarcinoma (PDAC) is still one of the most aggressive solid malignancies with a poor prognosis. Obesity and type 2 diabetes mellitus (T2DM) are two major risk factors linked to the development and progression of PDAC, both often characterized by high blood glucose levels. Macro...

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Detalles Bibliográficos
Autores principales: Otto, Lilli, Rahn, Sascha, Daunke, Tina, Walter, Frederik, Winter, Elsa, Möller, Julia Luisa, Rose-John, Stefan, Wesch, Daniela, Schäfer, Heiner, Sebens, Susanne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8151031/
https://www.ncbi.nlm.nih.gov/pubmed/34064969
http://dx.doi.org/10.3390/ijms22105086

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8151031/
https://www.ncbi.nlm.nih.gov/pubmed/34064969
http://dx.doi.org/10.3390/ijms22105086

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