Minimalistic In Vitro Culture to Drive Human Naive B Cell Differentiation into Antibody-Secreting Cells

High-affinity antibody-secreting cells (ASC) arise from terminal differentiation of B-cells after coordinated interactions with T follicular helper (Tfh) cells in germinal centers (GC). Elucidation of cues promoting human naive B-cells to progress into ASCs is challenging, as this process is notorio...

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Detalles Bibliográficos
Autores principales: Unger, Peter-Paul A., Verstegen, Niels J. M., Marsman, Casper, Jorritsma, Tineke, Rispens, Theo, ten Brinke, Anja, van Ham, S. Marieke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8151070/
https://www.ncbi.nlm.nih.gov/pubmed/34066151
http://dx.doi.org/10.3390/cells10051183

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8151070/
https://www.ncbi.nlm.nih.gov/pubmed/34066151
http://dx.doi.org/10.3390/cells10051183

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