Diet-Induced Obesity Impairs Outcomes and Induces Multi-Factorial Deficiencies in Effector T Cell Responses Following Anti-CTLA-4 Combinatorial Immunotherapy in Renal Tumor-Bearing Mice

SIMPLE SUMMARY: Immunotherapy use has become standard for many patients with advanced kidney cancer; unfortunately, <50% of patients experience durable responses. Mounting evidence suggests that modifiable factors, such as diet and obesity, impact immunotherapy outcomes. Obesity, a major U.S. hea...

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Detalles Bibliográficos
Autores principales: Turbitt, William J., Boi, Shannon K., Gibson, Justin T., Orlandella, Rachael M., Norian, Lyse A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8151089/
https://www.ncbi.nlm.nih.gov/pubmed/34064933
http://dx.doi.org/10.3390/cancers13102295

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8151089/
https://www.ncbi.nlm.nih.gov/pubmed/34064933
http://dx.doi.org/10.3390/cancers13102295

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