Drug Target Identification with Machine Learning: How to Choose Negative Examples

Identification of the protein targets of hit molecules is essential in the drug discovery process. Target prediction with machine learning algorithms can help accelerate this search, limiting the number of required experiments. However, Drug-Target Interactions databases used for training present hi...

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Detalles Bibliográficos
Autores principales: Najm, Matthieu, Azencott, Chloé-Agathe, Playe, Benoit, Stoven, Véronique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8151112/
https://www.ncbi.nlm.nih.gov/pubmed/34066072
http://dx.doi.org/10.3390/ijms22105118

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8151112/
https://www.ncbi.nlm.nih.gov/pubmed/34066072
http://dx.doi.org/10.3390/ijms22105118

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