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Technologies for High-Throughput Identification of Antibiotic Mechanism of Action

There are two main strategies for antibiotic discovery: target-based and phenotypic screening. The latter has been much more successful in delivering first-in-class antibiotics, despite the major bottleneck of delayed Mechanism-of-Action (MOA) identification. Although finding new antimicrobial compo...

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Detalles Bibliográficos
Autores principales: da Cunha, Bernardo Ribeiro, Zoio, Paulo, Fonseca, Luís P., Calado, Cecília R. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8151116/
https://www.ncbi.nlm.nih.gov/pubmed/34065815
http://dx.doi.org/10.3390/antibiotics10050565