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Technologies for High-Throughput Identification of Antibiotic Mechanism of Action
There are two main strategies for antibiotic discovery: target-based and phenotypic screening. The latter has been much more successful in delivering first-in-class antibiotics, despite the major bottleneck of delayed Mechanism-of-Action (MOA) identification. Although finding new antimicrobial compo...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8151116/ https://www.ncbi.nlm.nih.gov/pubmed/34065815 http://dx.doi.org/10.3390/antibiotics10050565 |