Ethyl Pyruvate Attenuates Microglial NLRP3 Inflammasome Activation via Inhibition of HMGB1/NF-κB/miR-223 Signaling

Ethyl pyruvate is a molecule with anti-inflammatory and pro-metabolic effects. Ethyl pyruvate has been shown to ameliorate the clinical and pathological findings of neurodegenerative diseases such as Alzheimer’s and Parkinson’s Diseases in rodents. Its anti-inflammatory and neuroprotective effects a...

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Detalles Bibliográficos
Autores principales: Olcum, Melis, Tufekci, Kemal Ugur, Durur, Devrim Yagmur, Tastan, Bora, Gokbayrak, Irem Nur, Genc, Kursad, Genc, Sermin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8151120/
https://www.ncbi.nlm.nih.gov/pubmed/34066647
http://dx.doi.org/10.3390/antiox10050745

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8151120/
https://www.ncbi.nlm.nih.gov/pubmed/34066647
http://dx.doi.org/10.3390/antiox10050745

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