Genetic and Epigenetic Alterations of CDH1 Regulatory Regions in Hereditary and Sporadic Gastric Cancer

E-cadherin is a key player in gastric cancer (GC) and germline alterations of CDH1, its encoding gene, are responsible for Hereditary Diffuse Gastric Cancer (HDGC) syndrome. This study aimed at elucidating the role of genetic variants and DNA methylation of CDH1 promoter and enhancers in the regulat...

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Detalles Bibliográficos
Autores principales: Tedaldi, Gianluca, Molinari, Chiara, São José, Celina, Barbosa-Matos, Rita, André, Ana, Danesi, Rita, Arcangeli, Valentina, Ravegnani, Mila, Saragoni, Luca, Morgagni, Paolo, Rebuzzi, Francesca, Canale, Matteo, Pignatta, Sara, Ferracci, Elisa, Martinelli, Giovanni, Ranzani, Guglielmina Nadia, Oliveira, Carla, Calistri, Daniele, Ulivi, Paola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8151134/
https://www.ncbi.nlm.nih.gov/pubmed/34066170
http://dx.doi.org/10.3390/ph14050457

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8151134/
https://www.ncbi.nlm.nih.gov/pubmed/34066170
http://dx.doi.org/10.3390/ph14050457

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