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Pharmacogenetics of the Central Nervous System—Toxicity and Relapse Affecting the CNS in Pediatric Acute Lymphoblastic Leukemia

SIMPLE SUMMARY: Despite recent improvements in cure rates, pediatric acute lymphoblastic leukemia (ALL) patients remain at risk to develop relapse disease or suffer from therapy-associated side effects. Over 5% of adverse events appear in the central nervous system (CNS) and can impact survival or q...

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Detalles Bibliográficos
Autores principales: Sági, Judit C., Gézsi, András, Egyed, Bálint, Jakab, Zsuzsanna, Benedek, Noémi, Attarbaschi, Andishe, Köhrer, Stefan, Sipek, Jakub, Winkowska, Lucie, Zaliova, Marketa, Anastasopoulou, Stavroula, Wolthers, Benjamin Ole, Ranta, Susanna, Szalai, Csaba, Kovács, Gábor T., Semsei, Ágnes F., Erdélyi, Dániel J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8151239/
https://www.ncbi.nlm.nih.gov/pubmed/34066083
http://dx.doi.org/10.3390/cancers13102333