Molecular and Cellular Mechanisms Driving Cardiovascular Disease in Hutchinson-Gilford Progeria Syndrome: Lessons Learned from Animal Models

Hutchinson-Gilford progeria syndrome (HGPS) is a rare genetic disease that recapitulates many symptoms of physiological aging and precipitates death. Patients develop severe vascular alterations, mainly massive vascular smooth muscle cell loss, vessel stiffening, calcification, fibrosis, and general...

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Detalles Bibliográficos
Autores principales: Benedicto, Ignacio, Dorado, Beatriz, Andrés, Vicente
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8151355/
https://www.ncbi.nlm.nih.gov/pubmed/34064612
http://dx.doi.org/10.3390/cells10051157

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8151355/
https://www.ncbi.nlm.nih.gov/pubmed/34064612
http://dx.doi.org/10.3390/cells10051157

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