Effect of F16-Betulin Conjugate on Mitochondrial Membranes and Its Role in Cell Death Initiation

This work demonstrates the effects of a newly synthesized conjugate of the plant triterpenoid betulin and the penetrating cation F16 used for mitochondrial targeting. The resulting F16-betulin conjugate revealed a mitochondria-targeted effect, decreasing the mitochondrial potential and inducing supe...

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Detalles Bibliográficos
Autores principales: Dubinin, Mikhail V., Semenova, Alena A., Nedopekina, Darya A., Davletshin, Eldar V., Spivak, Anna Yu., Belosludtsev, Konstantin N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8151401/
https://www.ncbi.nlm.nih.gov/pubmed/34068772
http://dx.doi.org/10.3390/membranes11050352

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8151401/
https://www.ncbi.nlm.nih.gov/pubmed/34068772
http://dx.doi.org/10.3390/membranes11050352

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