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The Synthesis and Evaluation of Multivalent Glycopeptoids as Inhibitors of the Adhesion of Candida albicans

Multivalency is a strategy commonly used by medicinal carbohydrate chemists to increase the affinity of carbohydrate-based small molecules for their protein targets. Although this approach has been very successful in enhancing binding to isolated carbohydrate-binding proteins, anticipating the multi...

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Detalles Bibliográficos
Autores principales: Martin, Harlei, Masterson, Hannah, Kavanagh, Kevin, Velasco-Torrijos, Trinidad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8151480/
https://www.ncbi.nlm.nih.gov/pubmed/34066787
http://dx.doi.org/10.3390/pathogens10050572