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Acid Sensing Ion Channel 2a Is Reduced in the Reduced Uterine Perfusion Pressure Mouse Model and Increases Seizure Susceptibility in Pregnant Mice

Eclampsia is diagnosed in pregnant women who develop novel seizures. Our laboratory showed that the reduced uterine perfusion pressure (RUPP) rat model of preeclampsia displays reduced latency to drug-induced seizures. While acid sensing ion channels (ASIC1a and 3) are important for reducing seizure...

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Detalles Bibliográficos
Autores principales: Jones-Muhammad, Maria, Shao, Qingmei, Cain-Shields, Loretta, Shaffery, James P., Warrington, Junie P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8151496/
https://www.ncbi.nlm.nih.gov/pubmed/34066660
http://dx.doi.org/10.3390/cells10051135