Downregulation of ATM and BRCA1 Predicts Poor Outcome in Head and Neck Cancer: Implications for ATM-Targeted Therapy

ATM and BRCA1 are DNA repair genes that play a central role in homologous recombination repair. Alterations of ATM and BRCA1 gene expression are found in cancers, some of which are correlated with treatment response and patient outcome. However, the role of ATM and BRCA1 gene expression in head and...

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Detalles Bibliográficos
Autores principales: Wang, Yu-Chu, Lee, Ka-Wo, Tsai, Yi-Shan, Lu, Hsing-Han, Chen, Si-Yun, Hsieh, Hsin-Ying, Lin, Chang-Shen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8151497/
https://www.ncbi.nlm.nih.gov/pubmed/34068585
http://dx.doi.org/10.3390/jpm11050389

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8151497/
https://www.ncbi.nlm.nih.gov/pubmed/34068585
http://dx.doi.org/10.3390/jpm11050389

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