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Mitochondrial D-Loop Region Methylation and Copy Number in Peripheral Blood DNA of Parkinson’s Disease Patients

Altered mitochondrial DNA (mtDNA) methylation has been detected in several human pathologies, although little attention has been given to neurodegenerative diseases. Recently, altered methylation levels of the mitochondrial displacement loop (D-loop) region, which regulates mtDNA replication, were o...

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Detalles Bibliográficos
Autores principales: Stoccoro, Andrea, Smith, Adam R., Baldacci, Filippo, Del Gamba, Claudia, Lo Gerfo, Annalisa, Ceravolo, Roberto, Lunnon, Katie, Migliore, Lucia, Coppedè, Fabio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8151519/
https://www.ncbi.nlm.nih.gov/pubmed/34065874
http://dx.doi.org/10.3390/genes12050720