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Personalized Medicine for Neuroblastoma: Moving from Static Genotypes to Dynamic Simulations of Drug Response

High-risk neuroblastoma is an aggressive childhood cancer that is characterized by high rates of chemoresistance and frequent metastatic relapse. A number of studies have characterized the genetic and epigenetic landscape of neuroblastoma, but due to a generally low mutational burden and paucity of...

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Detalles Bibliográficos
Autores principales: Han, Jeremy Z. R., Hastings, Jordan F., Phimmachanh, Monica, Fey, Dirk, Kolch, Walter, Croucher, David R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8151552/
https://www.ncbi.nlm.nih.gov/pubmed/34064704
http://dx.doi.org/10.3390/jpm11050395