Combinations of Freeze-Dried Amorphous Vardenafil Hydrochloride with Saccharides as a Way to Enhance Dissolution Rate and Permeability

To improve physicochemical properties of vardenafil hydrochloride (VAR), its amorphous form and combinations with excipients—hydroxypropyl methylcellulose (HPMC) and β-cyclodextrin (β-CD)—were prepared. The impact of the modification on physicochemical properties was estimated by comparing amorphous...

Descripción completa

Detalles Bibliográficos
Autores principales: Wiergowska, Gabriela, Ludowicz, Dominika, Wdowiak, Kamil, Miklaszewski, Andrzej, Lewandowska, Kornelia, Cielecka-Piontek, Judyta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8151567/
https://www.ncbi.nlm.nih.gov/pubmed/34064796
http://dx.doi.org/10.3390/ph14050453

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8151567/
https://www.ncbi.nlm.nih.gov/pubmed/34064796
http://dx.doi.org/10.3390/ph14050453

Ejemplares similares